解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVES:Low-dose methoxyflurane is a non-opioid, inhaled analgesic administered via the Penthrox inhaler and was recently licensed in Europe for emergency relief of moderate-to-severe trauma-associated pain in conscious adults. This non-interventional study investigated occupational exposure to methoxyflurane in the...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034647
更新日期:2020-02-10 00:00:00
abstract:OBJECTIVES:Mortality rates in Scotland are higher, and health inequalities are greater, than in the rest of Western and Central Europe. There was a marked divergence during the 1980s and 1990s in the Scottish rates partly due to rises in alcohol-related and drug-related deaths, suicide and deaths by assault. This study...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030064
更新日期:2020-02-09 00:00:00
abstract:INTRODUCTION:Hospitals are complex systems and optimising their function is critical to the provision of high quality, cost effective healthcare. Metrics of performance have to date focused on the performance of individual elements rather than the whole system. Manipulation of individual elements of a complex system wi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034265
更新日期:2020-02-09 00:00:00
abstract:OBJECTIVES:Improving outcomes for older people with long-term conditions and multimorbidity is a priority. Current policy commits to substantial expansion of social prescribing to community assets, such as charity, voluntary or community groups. We use longitudinal data to add to the limited evidence on whether this is...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033186
更新日期:2020-02-06 00:00:00
abstract:OBJECTIVES:Bariatric surgery is the most clinically effective treatment for people with severe and complex obesity, however, the psychosocial outcomes are less clear. Follow-up care after bariatric surgery is known to be important, but limited guidance exists on what this should entail, particularly related to psycholo...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035013
更新日期:2020-02-06 00:00:00
abstract:OBJECTIVES:Patient-centred care is related to better health outcomes, greater patient satisfaction and reduced healthcare costs. One of the core components of patient-centred care, defined in the patient-centred clinical method, is enhancing the patient-doctor relationship. In this study, we aim to measure the therapeu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033710
更新日期:2020-02-05 00:00:00
abstract:INTRODUCTION:Cancer is one of the leading causes of death globally and many jurisdictions have developed population-based cancer screening programmes to reduce the public health burden of disease. However, screening participation remains suboptimal. Social media and other mobile health (mHealth) technologies are increa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035411
更新日期:2020-02-05 00:00:00
abstract:INTRODUCTION:One potential stressor that can affect preimplantation and postimplantation embryonic growth after in vitro fertilisation (IVF) is the pH of the human embryo culture medium, but no evidence exists to indicate which pH level is optimal for IVF. Based on anecdotal evidence or mouse models, culture media manu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034194
更新日期:2020-02-04 00:00:00
abstract:OBJECTIVE:Since 2011 China's central government has committed to establishing a new 'general practitioner' (GP)-centred primary care system. To this end there have been great efforts to train an additional 300 000 GPs by 2020. This paper examines the perspective of practitioners in Henan, China, regarding general pract...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036240
更新日期:2020-02-03 00:00:00
abstract:OBJECTIVES:To understand the challenges faced by patients with tuberculosis (TB) and factors that influence TB treatment adherence in Ukraine. DESIGN:Qualitative study. SETTING:TB treatment facilities in Kyiv Oblast, Ukraine. PARTICIPANTS:Sixty adults who had undergone treatment for drug-sensitive TB between June 20...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032027
更新日期:2020-02-02 00:00:00
abstract:INTRODUCTION:Excessive prescribing after surgery has contributed to a public health crisis of opioid addiction and overdose in North America. However, the value of prescribing opioids to manage postoperative pain after surgical discharge remains unclear. We propose a systematic review and meta-analysis to assess the ex...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035443
更新日期:2020-02-02 00:00:00
abstract:INTRODUCTION:Among preterm infants, mother's own milk feeding reduces neonatal morbidity and decreases the length of hospital stay. However, breastfeeding rates and duration are lower than among term infants. It is reported that peer counselling is effective in increasing breast feeding in term infants in low-income an...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032910
更新日期:2020-01-30 00:00:00
abstract:INTRODUCTION:Multimorbidity is a major challenge for current healthcare systems and professionals. From the different approaches that have been proposed to analyse this issue, the hypothesis of the existence of association patterns of different chronic conditions is gaining visibility. In addition, multimorbidity can b...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2019-033322
更新日期:2020-01-26 00:00:00
abstract:OBJECTIVES:To analyse the association of sedentary behaviour patterns with dietary and lifestyle habits among public school teachers. DESIGN:Cross-sectional study. PARTICIPANTS:A sample of 245 teachers (186 women and 59 men) with mean age of 45.2 (±10.4) were randomly selected from public schools. PRIMARY AND SECOND...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034322
更新日期:2020-01-23 00:00:00
abstract:OBJECTIVES:To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials. DESIGN:Cross-sectional study. SE...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034666
更新日期:2020-01-22 00:00:00
abstract:OBJECTIVES:Understanding patients' preferences for treatment is crucial to provision of good care and shared decisions, especially when more than one treatment option exists for a given condition. One such condition is infection of the area around the prosthesis after hip replacement, which affects between 0.4% and 3% ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031645
更新日期:2020-01-21 00:00:00
abstract:INTRODUCTION:The health workforce is an integral component of the healthcare system. Comprehensive, high-quality data on the health workforce are essential to identifying gaps in health service provision, as well as informing future health workforce and health services planning, and health policy. While many data sourc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034400
更新日期:2020-01-21 00:00:00
abstract:INTRODUCTION:One in four diabetes patients will develop a foot ulcer over their lifetime. The role of glycaemic control in the healing of foot ulcers in diabetes patients is not supported by randomised controlled trial (RCT) data. OBJECTIVES:To determine the feasibility of an RCT of glycaemic control with intensive in...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029009
更新日期:2020-01-20 00:00:00
abstract:OBJECTIVE:Nearly 100 000 primary total knee replacements (TKR) are performed in the UK annually. The primary aim of TKR is pain relief, but 10%-34% of patients report chronic pain. The aim of this systematic review was to evaluate the effectiveness of presurgical interventions in preventing chronic pain after TKR. DES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033248
更新日期:2020-01-20 00:00:00
abstract:OBJECTIVES:Transgender women (TW) are highly burdened by HIV infection in the USA. Research is needed into drivers of the HIV epidemic for TW, including longitudinal studies to identify risks for incident HIV infection and optimal intervention targets. This formative research sought to understand TW's experiences with,...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029852
更新日期:2020-01-19 00:00:00
abstract:INTRODUCTION:Despite the significant disease burden of bronchiectasis in Korea, no large-scale, representative prospective cohort studies have been conducted to evaluate the clinical characteristics of Korean patients with bronchiectasis, indicating an urgent need for cohort studies on bronchiectasis. METHODS AND ANAL...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034090
更新日期:2020-01-19 00:00:00
abstract:OBJECTIVE:To assess the 24-month cost-effectiveness of total knee replacement (TKR) plus non-surgical treatment compared with non-surgical treatment with the option of later TKR if needed. METHODS:100 adults with moderate-to-severe knee osteoarthritis found eligible for TKR by an orthopaedic surgeon in secondary care ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033495
更新日期:2020-01-15 00:00:00
abstract:OBJECTIVE:In this study, we assess the performance of public hospitals in Saudi Arabia. We detect the sources of inefficiency and estimate the optimal levels of the resources that provide the current level of health services. We enrich our analysis by employing locations and capacities of the hospitals. DESIGN:We empl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031924
更新日期:2020-01-12 00:00:00
abstract:OBJECTIVES:To investigate the association between maternal employment precarity and infant low birth weight (LBW), and to assess if this association differs by race/ethnicity. METHODS:Data were collected from 2871 women enrolled in the National Longitudinal Survey of Youth 1979 and the National Longitudinal Survey of ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029584
更新日期:2020-01-09 00:00:00
abstract:OBJECTIVES:To evaluate the readiness to implement the Falsified Medicines Directive (FMD) by community pharmacies in England. Eight secondary objectives were assessed. SETTING:Community/retail pharmacies. PARTICIPANTS:We invited pharmacists from 501 pharmacies to complete a survey. Non-contractors, non-pharmacists or...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033405
更新日期:2020-01-09 00:00:00
abstract:INTRODUCTION:Fracture healing can fail in up to 10% of cases despite appropriate treatment. While lithium has been the standard treatment for bipolar disorder, it may also have a significant impact to increase bone healing in patients with long bone fractures. To translate this knowledge into clinical practice, a rando...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031545
更新日期:2020-01-07 00:00:00
abstract:BACKGROUND:Dual antiplatelet therapy (DAPT) is frequently discontinued after drug-eluting stent (DES) implantation, which could increase the risk of major adverse cardiovascular events (MACEs). Few studies have attempted to improve DAPT adherence through web-based social media. OBJECTIVE:To explore the effect of socia...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033017
更新日期:2020-01-07 00:00:00
abstract:INTRODUCTION:Acute pancreatitis (AP) is a life-threatening inflammatory disease of the exocrine pancreas which needs acute hospitalisation. Despite its importance, we have significant lack of knowledge whether the lifestyle factors elevate or decrease the risk of AP or influence the disease outcome. So far, no syntheti...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029660
更新日期:2020-01-06 00:00:00
abstract:OBJECTIVES:To define the core competencies essential for specialist training in neurocritical care in China. DESIGN:Modified Delphi method and nominal group (NG) technique. SETTING:National. PARTICIPANTS:A total of 1094 respondents from 33 provinces in China participated in the online survey. A NG of 11 members was ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033441
更新日期:2020-01-06 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the combined effect of exposure to perceived risk at work and unstable employment on self-rated health in both Korea and the European Union. DESIGN:Cross-sectional study. SETTING:We conducted the analyses using employees data from the third Korean Working Condit...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032380
更新日期:2020-01-02 00:00:00
abstract:OBJECTIVE:To explore the perspectives of primary healthcare (PHC) professionals providing care to refugees through mainstream general practice. DESIGN:Qualitative exploratory design with semistructured interviews subjected to inductive thematic analysis. SETTING AND PARTICIPANTS:Nine general practices enrolled in the...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034323
更新日期:2019-12-31 00:00:00
abstract:OBJECTIVES:We evaluated the effectiveness and tolerability of linaclotide, a minimally absorbed guanylate cyclase-C agonist, in patients with irritable bowel syndrome with constipation (IBS-C) in routine clinical practice. SETTING:A multicentre, non-interventional study conducted between December 2013 and November 201...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-025627
更新日期:2019-12-30 00:00:00
abstract:INTRODUCTION:Health professions need to prepare for the increase of older patients with osteoarthritis requiring health services including those requiring total joint arthroplasty (TJA). The primary objective of this study is to assess the effect of a tailored prehabilitation programme of older patients awaiting primar...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2019-031626
更新日期:2019-12-30 00:00:00
abstract:OBJECTIVES:Identifying the issues and concerns that matter most to burns survivors can be challenging. For a number of reasons, but mainly relating to patient empowerment, some of the most pressing concerns patients may have during a clinical encounter may not naturally be the focal point of that encounter. The Patient...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032785
更新日期:2019-12-30 00:00:00
abstract:OBJECTIVE:To determine the housing situation among people seeking psychiatric treatment in relation to morbidity and service utilisation. DESIGN:Cross-sectional patient survey. SETTING:Psychiatric centre with a defined catchment area in Berlin, Germany, March-September 2016. PARTICIPANTS:540 psychiatric inpatients i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032576
更新日期:2019-12-29 00:00:00
abstract:OBJECTIVES:The aim of the study was to explore what components of the General Medical Council's (GMC) Quality Assurance Framework work, for whom, in what circumstances and how? SETTING:UK undergraduate and postgraduate medical education and training. PARTICIPANTS:We conducted interviews with a stratified sample of 36...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033614
更新日期:2019-12-29 00:00:00
abstract:OBJECTIVES:To assess the association between blood circulating vitamin D levels and colorectal cancer risk in the Asian population. DESIGN:This is a systematic review and dose-response meta-analysis of observational studies that investigated the relationship between blood circulating vitamin D levels and colorectal ca...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2019-030513
更新日期:2019-12-23 00:00:00
abstract:INTRODUCTION:Depressive disorders are very common diseases entailing a great burden on affected people. However, comprehensive information on long-term disease course in patients with severe depression is lacking so far. The objectives of the DELTA study are to examine long-term outcomes and their predicting factors, t...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032507
更新日期:2019-12-23 00:00:00
abstract:INTRODUCTION:Physical activity is an integral part of healthy ageing, yet the majority of older adults 65+ years are not sufficiently active. Web-based physical activity interventions hold much promise to reach older adults. Preliminary evidence suggests that web-based interventions with tailored advice and Fitbits may...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033305
更新日期:2019-12-23 00:00:00
abstract:OBJECTIVES:To investigate if the treatment effect of antidepressants in patients with depression substantially varies in each patient (patient-by-treatment interaction or treatment heterogeneity), a necessary but largely unexplored prerequisite of personalised antidepressant treatment. DESIGN:Meta-analytic variance co...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2019-034816
更新日期:2019-12-23 00:00:00